Purine nucleosides
Medchemexpress LLC 2'-Deoxyguanosine monohydrate | 312693-72-4 | 99.7% | 10 UMOL
2'-Deoxyguanosine monohydrate is a nucleoside composed of guanine and 2'-deoxyribose, serving as a fundamental structural unit of DNA. Its oxidation products may contribute to DNA damage, which can consequently affect gene expression or induce cancer. This product is intended for research use only.
- Molecular weight: 285.26
- Formula: C10H15N5O5
- Appearance: Solid
- Color: White to off-white
Medchemexpress LLC 2'-Deoxyguanosine | 961-07-9 | 100.0% | 267.25 | 25 MG
2'-Deoxyguanosine is a purine nucleoside with various biological activities. It can induce DNA division in mouse thymus cells and acts as a potent cell division inhibitor in plant cells. It also demonstrates antiproliferative and antiviral effects against several cell lines and viruses.
- Induces DNA division in mouse thymus cells.
- Acts as a potent cell division inhibitor in plant cells.
- Inhibits clonal growth of HL-60 and K562 leukemia cells.
- Exhibits antiviral activity against varicella zoster virus (VZV) Oka strain.
- Exhibits antiviral activity against human cytomegalovirus (HCMV) AD 169 strain.
- Exhibits antiviral activity against herpes simplex virus-1 VR-3 strain.
- Exhibits antiviral activity against herpes simplex virus-2 (HSV-2) Ms strain.
Medchemexpress LLC 2'-Deoxyadenosine monohydrate | 16373-93-6 | 99.9% | 269.26 | 10 G
2′-Deoxyadenosine monohydrate is an adenine nucleoside that inhibits glucose-stimulated insulin release and glucose-stimulated increases in islet cyclic AMP (cAMP) accumulation. It activates caspase-3 and promotes apoptosis, and inhibits the activity of S-adenosyl-L-homocysteine hydrolase (SAHH). This compound can inhibit the growth of various cells and has an anticancer effect on colon cancer.
- Inhibits glucose-stimulated insulin release
- Activates caspase-3 and promotes apoptosis
- Inhibits S-adenosyl-L-homocysteine hydrolase (SAHH) activity
- Inhibits the growth of various cells
- Demonstrates an anticancer effect on colon cancer
- For research use only
Cambridge Isotope Laboratories 8-Hydroxy-2-deoxyguanosine (unlabeled) 25 ug/mL in water 1 2 mL
8-Hydroxy-2-deoxyguanosine (unlabeled) 25 ug/mL in water 1 2 mL
Medchemexpress LLC 2'-Deoxyadenosine-5'-triphosphate trisodium | 54680-12-5 | 99.0% | 557.13 | 5 ML
2'-Deoxyadenosine-5'-triphosphate trisodium is a raw material used by DNA polymerase to synthesize long DNA chains during DNA replication. It is also utilized in reverse transcription polymerase chain reaction (RT-PCR) for DNA amplification. This product is provided as an aqueous solution.
- Raw material for DNA synthesis
- Utilized in reverse transcription polymerase chain reaction (RT-PCR)
- Provided as an aqueous solution
Medchemexpress LLC Guanosine, 8-bromo-2'-deoxy- | 13389-03-2 | ≥98.0% | 346.14 | 1 ML
8-Bromo-2'-deoxyguanosine is an inflammation-related DNA halogenated adduct and early biomarker of oxidative tissue damage. It serves as an immunogen for mAb8B3, detecting DNA modifications. Elevated urinary levels occur in inflammatory disease models. Used in studies for inflammatory diseases, diabetes, hepatocellular carcinoma, and UV-B induced skin inflammation.
- Inflammation-related DNA halogenated adduct.
- Early biomarker of inflammation-induced oxidative tissue damage.
- Immunogen for mAb8B3 monoclonal antibody.
- Urinary levels increase in inflammatory disease models.
- Applications in inflammatory diseases, diabetes, hepatocellular carcinoma, UV-B induced skin inflammation.
- High, specific cross-reactivity with mAb8B3 in competitive indirect ELISA.
eMolecules 892-48-8 | 5'-Chloro-5'-deoxyadenosine | Chemodex Ltd. | MFCD00049038 | 285.690 | C10H12ClN5O3 | 95.000 | Nc1ncnc2n(cnc12)[C@@H]1O[C@H](CCl)[C@@H](O)[C@H]1O | 100mg | 482921721
5'-Chloro-5'-deoxyadenosine | Chemodex Ltd. | 892-48-8 | MFCD00049038 | 285.690 | C10H12ClN5O3 | 95.000 | Nc1ncnc2n(cnc12)[C@@H]1O[C@H](CCl)[C@@H](O)[C@H]1O | 100mg | 482921721
Medchemexpress LLC Guanosine-1′-13C, 2′-deoxy-, monohydrate | 478511-26-1 | 99.9% | 286.25 | C913CH15N5O5 | 1 MG
2'-Deoxyguanosine-13C monohydrate is a 13C-labeled form of the nucleoside 2'-deoxyguanosine supplied as the monohydrate for analytical and research applications. It is intended for use as a stable-isotope internal standard, tracer, or reference material in mass spectrometry and metabolic studies. Certificate of analysis and safety data sheet are available for lot-specific purity and storage information.
- Isotope-labeled (13C) monohydrate suitable for analytical standards and tracing.
- High purity: 99.9% by HPLC, reported on the certificate of analysis.
- Supplied as a solid in small milligram quantities for laboratory use.
- Common applications include LC-MS/MS internal standard and metabolic labeling.
- Certificate of analysis and safety data sheet available for handling and storage instructions.
Medchemexpress LLC Guanosine-1',2,2',3',4,4',5,5',6,8-13C10, 2'-deoxy- | 1245539-86-9 | 99.8% | 277.17 | 1 MG
2'-Deoxyguanosine-13C10 is a 13C-labeled version of 2'-Deoxyguanosine. It is a purine nucleoside with various biological activities, capable of inducing DNA division in mouse thymus cells and acting as a cell division inhibitor in plant cells. In vitro, it inhibits the clonal growth of HL-60 and K562 leukemia cells.
- 13C-labeled version of 2'-Deoxyguanosine
- Induces DNA division in mouse thymus cells
- Potent cell division inhibitor in plant cells
- Inhibits clonal growth of HL-60 and K562 leukemia cells
Cayman Chemical 2-Fluoro-2-deoxyadenosIn 1g
A prodrug form of 2-F-adenine; reduces mean tumor weight in an E. coli purine nucleoside phosphorylase-expressing D54 glioblastoma mouse xenograft model at 100 mg/kg
Medchemexpress LLC Adenosine, 2-amino-2'-deoxy- | 4546-70-7 | MFCD00047240 | 99.6% | 266.26 g·mol⁻¹ | C10H14N6O3 | 5 G
2-Amino-2'-deoxyadenosine is a modified deoxyribonucleoside (CAS 4546-70-7) used as a building block in oligonucleotide synthesis and nucleic acid research. Supplied for research use only, it is offered in solid and solution formats and accompanied by analytical documentation to support quality and reproducibility.
- High purity (99.6%).
- Available in multiple sizes, including 5 g and solution formats.
- Molecular weight 266.26 g·mol⁻¹; formula C10H14N6O3.
- Certificate of analysis available for batch verification.
- Intended for research use only; not for human or veterinary use.
TARGETMOL CHEMICALS INC 3-DEOXYGUANOSINE 100MG
Also available in 10 mg 25 mg 50 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. 3'-Deoxyguanosine is a ligand that can be complexed with enzymes such as purine nucleoside phosphorylase and receptors. purity: 98%
Medchemexpress LLC 2′-deoxyguanosine 5′-monophosphate-13C10,15N5 dilithium | MFCD00057076 | 99.8% | 373.98 g/mol | 13C10H12Li215N5O7P | 10 MG
2′-Deoxyguanosine 5′-monophosphate-13C10,15N5 dilithium is an isotopically labeled nucleotide provided as the dilithium salt. It is intended for use as a tracer and internal standard in quantitative analyses by NMR, GC-MS, and LC-MS, and is supplied in small, pre-weighed pack sizes suitable for preparing standard solutions.
Medchemexpress LLC 2'-Deoxyadenosine 5'-triphosphate disodium | 74299-50-6 | MFCD00080335 | 99.97% | 535.15 | 50 MG
2'-Deoxyadenosine 5'-triphosphate disodium is a nucleotide with important biological activities. It plays a key role in DNA synthesis and reverse transcription and is widely utilized in in vitro reactions in molecular biology research.
- Serves as a substrate for various polymerases
- Supports DNA synthesis
- Supports reverse transcription
- Suitable for in vitro reactions in molecular biology research